Anouck Jue

Aim: to compare autogenous bone (AB) versus bovine bone mineral (BBM) (Cerabone) with locally harvested AB chips for a maxillary sinus floor augmentation (MFSA) procedure in terms of implant survival, clinical success and patient reported outcome measures (PROMs). Materials and methods: Patients in need for bilateral MFSA prior to the placement of dental implants were recruited for this multicenter split-mouth randomized controlled clinical trial. Bilateral MFSA was performed after random allocation for the AB side or the BBM side. Grafts were taken from the mandibular ramus (AB) or locally harvested (BBM) during the MFSA procedure. Implants were placed 4-6 months after MFSA. Follow-up was performed 12 months after loading. Outcome measures were implant survival and complications, clinical success, clinical indices for plaque, bleeding, width of the mucosa, pockets and PROMs. Results: In total, 50 patients were included and 197 implants were placed (AB= 98, BBM=99). Implant survival after 12 months was 91.3% for the AB-group and 96.7% for the BBM-group. There were no significant differences in complications between the two groups (p=0.990). The clinical success was 89.5% for the AB-group and 93.3% for the BBM-group (RR= 0.64, 95% CI 0.24 to 1.71; p=0.358). There were no significant differences in clinical indices between the groups. Patient satisfaction was significantly better at follow-up compared to baseline (p<0.005). The majority of the patients reported pain and swelling after MFSA and implant placement and temporary dysesthesia of the lower lip was found in four patients after grafting from the mandibular ramus. Conclusion: Implants placed in the maxilla after MFSA with AB or BBM showed comparable survival and clinical success outcomes and satisfied patients 12 months after loading. However, BBM with locally harvested AB bone chips might lead to less patient morbidity.

My name is Anouck Jue and I am a 24-year old Dentistry student at the Academic Center for Dentistry Amsterdam, ACTA. I will graduate this summer and coming September I will start my bachelor of Medicine at the Erasmus University Rotterdam, since it is my ambition to become a maxillofacial surgeon. I have been working at a general dental practice in Rotterdam for three years now and I did various internships with a focus on Special Dental care and Maxillofacial Prosthetics. I just finished my masters thesis concerning implantology in the resorbed maxilla at the department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics at the Erasmus Medical Center Rotterdam. This study is the start of my PhD on oral implantology and bone substitutes.