Mario Romandini

Aim. To evaluate long-term outcomes and prognostic factors of surgical treatment of peri-implantitis. Materials and Methods. 149 patients (267 implants) were surgically treated for peri-implantitis and followed for an average of 7.0 (SD: 3.6) years. The primary outcome was implant loss. Additional bone loss and renewed surgical interventions were secondary outcomes. Patient/implant characteristics, as well as clinical and radiographic parameters collected prior to initial surgery were evaluated as potential predictors of implant loss. Flexible parametric survival models using restricted cubic spline functions were used; 5- and 10-year predicted rates of implant loss were calculated according to different scenarios. Results. 53 implants (19.9%) in 35 patients (23.5%) were lost during the observation period. Implant loss occurred after a mean period of 4.4 (SD: 3.0) years and was predicted by implant surface characteristics (modified surface; HR 4.5), implant length (HR 0.8 by mm), suppuration at baseline (HR 2.7) and disease severity (baseline bone loss: HR 1.2 by mm). Estimates of 5- and 10-year implant loss ranged from 1% (best prognostic scenario) to 63% (worst prognostic scenario) and from 3% to 89%, respectively. Renewed surgical therapy was performed at 65 implants (24.3%) in 36 patients (24.2%) after a mean time period of 4.5 (3.1) years. In all, 59.5% of implants showed additional bone loss, were surgically retreated or lost. Conclusions. Recurrence of disease is common following surgical treatment of peri-implantitis. The strongest predictor for implant loss was implant surface characteristics. Implant length, as well as suppuration and disease severity at baseline were also relevant factors. Clinicians may consider these parameters in their personalized decision-making.

• Current position: Associate Professor in Periodontology – University of Oslo (EFP-accredited). • Degree in Dentistry (cum laude) at Catholic University of Rome (2013). • Specialist in Oral Surgery (cum laude) at the University of Chieti (2017). • MSc in Dental Science at Complutense University of Madrid (UCM) (2018). • Specialist in Periodontology and Implantology at UCM (2020) • PhD in Dentistry (cum laude) at UCM (June 2022). • Author of over 40 scientific publications on top-ranked journals. • Editorial Board member: Journal of Clinical Periodontology, Clinical Oral Implants Research, Frontiers in Dental Medicine. • Recipient of research grants, including: ITI (2021), Osteology (2015, 2016, 2019, 2021), SEPA (2020), Eklund (2019), Proclinic (2018). • Winner of research and clinical awards, including: 2nd EFP Prize for Clinical Research (2022), Osteology Best Research award (2018, 2022), PerioNext prize (2020), SIdP Vogel prize (2020). • Scientific boards: EAO Junior Academy, SIdP Young leading group, IAO Next Gen leading group. • Lecturer in international courses and congresses.