Hsuan-Hao, Chang

The aim of this study was to analyze the immune response to titanium implant and zirconia implant in peri-implant gingival tissue. And to evaluate T cell differentiation and inflammatory phenotypic change distant to the peri-implant microenvironment by implant induced lymphadenitis. The results showed that titanium dental implants can drive the T-cell immunity to a pro-inflammatory status not only in the peri-implant microenvironment but also in the peripheral lymphoid organs, which is the cervical lymph nodes in our case. Zirconia implants, which provoke less and more gentle immune response in both surrounding tissue and distant lymph nodes, might be a novel solution.

I am now a graduate student in Graduate Institute of Clinical Dentistry of National Taiwan University and had periodontology clinical training in National Taiwan University Hospital. I am now doing the research about the post-OP immune response of titanium implants and zirconia implants under Dr. Yi-Wen, Chen’s instruction. Hope to have the chance to discuss with all of you in person!